Fig. 6

Effect of varying the dissociation rate constants kdissD1 and kkdissD2 on the relationship between the fraction of activated AChRs, [ARA∗]peak/[ARA∗]max, and the receptor occupancy Ototal. a Results under the setting of [ A]init=0.1×[R]total corresponding to in vivo concentration. b Results under the setting of [ A]init=10×[R]total corresponding to in vitro concentration