Fig. 4

Effect of varying kinetic constants for ACh and NDNB on the relationship between the fraction of activated AChRs, [ARA∗]peak/[ARA∗]max, and the receptor occupancy Ototal. a Results of varying the equilibrium dissociation constants for ACh under KA=KA1=KA2 (κA1=κA2 and μA=1). b Results of varying the site-selectivity μD=KD1/KD2 of an NDNB