Fig. 5
From: Computational modeling of the effects of autophagy on amyloid-β peptide levels
Aβ secretion and clearance fluxes in normal and pathological conditions. Fsec and Fclr denote the Aβ secretion flux (from the intracellular to the extracellular space) and Aβ clearance flux in the extracellular space, respectively. The results in the second column have been obtained under 20-fold increase in the autophagosome formation rate constant (rg3 = 20 × rg3(0)), with other parameters kept unchanged