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Table 2 Estimated parameters using local and global optimization algorithms for the simple GMA system

From: Identification of metabolic system parameters using global optimization methods

Actual Parameters

Estimated parameters with varying bounds

 

0 %

10 %

100 %

200 %

500 %

 

Local

Global

Local

Global

Local

Global

Local

Global

Local

Global

0.8

0.8

0.8

0.8

0.8

0.799

0.799

-0.8

0.8

0.8

0.8

1.0

1.0

1.0

1.0

1.0

1.0

1.0

3.0

1.0

1.0

1.0

1.0

1.0

1.0

1.0

1.0

1.0

1.0

-1.0

1.0

1.0

1.0

3.0

3.0

3.0

3.0

3.0

2.99

2.99

-1.09

3.0

3.0

3.0

0.5

0.5

0.5

0.5

0.5

0.5

0.5

-0.45

0.5

0.5

0.5

0.1

0.1

0.1

0.1

0.1

0.1

0.1

0.3

0.1

0.1

0.1

2.0

2.0

2.0

2.0

2.0

2.0

2.0

1.019

2.0

2.0

1.999

0.75

0.75

0.75

0.75

0.75

0.75

0.75

-0.40

0.75

0.75

0.749

0.2

0.2

0.2

0.2

0.2

0.199

0.199

-0.2

0.2

0.2

0.2

1.5

1.5

1.5

1.5

1.5

1.499

1.499

-1.5

1.5

1.5

1.5

0.5

0.5

0.5

0.5

0.5

0.499

0.499

-0.5

0.499

0.5

0.499

5.0

5.0

5.0

5.0

5.0

5.0

5.0

6.074

5.0

5.0

4.999

0.5

0.5

0.5

0.5

0.5

0.499

0.499

0.611

0.499

0.5

0.5