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Figure 2 | Theoretical Biology and Medical Modelling

Figure 2

From: Breakdown of accommodation in nerve: a possible role for persistent sodium current

Figure 2

Relationship between the properties of persistent sodium channels and breakdown of accommodation: A) Number of persistent sodium channels (number of persistent sodium channels: 1.0%, 1.5%, 2.0%, 2.5%, and 3.0%). B) Voltage shift of the kinetics of the persistent sodium channels relative to the transient sodium channels (voltage shift: -0 mV, -5 mV, -10 mV, -15 mV, and -20 mV). C) Time constant of persistent sodium channel activation (time-constant slowed by a factor of: 10, 6.66, 4.5, 3.0, 2.0, and 1.0). A thick line and bold number indicates the default model.

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